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. 1999 Jul;127(6):1502–1510. doi: 10.1038/sj.bjp.0702691

Figure 7.

Figure 7

(A) The ET-18-OCH3-induced Ca2+ influx detected by Mn2+ quench measurements. The experiments were performed in Ca2+ medium plus 50 μM MnCl2. Solid trace: control response of ET-18-OCH3 (25 μM), applied at 30 s. Dashed trace: La3+ (0.1 mM) was added at 0 s followed by ET-18-OCH3 (25 μM) at 30 s. Excitation signal at 360 nm and emission signal at 510 nm were recorded. (B) Effect of La3+ on the ET-18-OCH3-induced [Ca2+]i rise. ET-18-OCH3 was added at 30 s in traces a–f and La3+ (0.1 mM) was added at 475 s in trace a, 265 s in trace b, 220 s in trace c, 205 s in trace d, 180 s in trace e and 0 s in trace f. Traces are typical of 3–4 experiments.