Immunohistochemical localisation of COX-1 isoenzyme in sections of colon, negative control (a). In normal colon, colonocytes of the upper half of the crypts were found to be COX-1-positive (b, c). COX-1 expression in the colon of TNBS-control rats (d, e). COX-1 expression of inflamed colon treated with resveratrol 10 mg kg−1 (f, g). Original magnifications × 10, × 20 and × 40.