Table 1.
Parameters quantified after administration of resveratrol (R: 10 mg kg−1) in rats with chronic colitis induced by TNBS intracolonic instillation (30 mg per animal)
| Group | n | Body weight changes (g) | Adhesions (score 0–2) | Stool consistency (score 0–1) | Colon weight/colon length (mg cm−1) |
|---|---|---|---|---|---|
| Sham | 10 | 88.3±16.4 | 0 | 0 | 12.1±0.8 |
| EtOH | 8 | 81.7±16.4 | 0 | 0 | 15.1±1.9 |
| TNBS | 10 | 76.0±20.7 | 1.8±0.2a,b | 0.6±0.2 | 30.4±8.4a |
| TNBS+R 10 | 11 | 78.6±13.6 | 1.6±0.1a,b | 0.3±0.2 | 22.3±2.0 |
n: number of animals per group
Colonic parameters were quantified in the sham group (n=10), which received saline instillation. TNBS group (n=8) received trinitrobenzene sulphonic acid intracolonically in a vehicle of 50% ethanol; ethanol group (n=8) received 50% ethanol intracolonic injection. Data are expressed as mean±s.e.m.
a
P<0.05 significantly different from sham.
b
P<0.05 significantly different from EtOH.