Table 1.
Summary of NMU-mediated smooth muscle contractile responses
| Rat | Mouse | |||
|---|---|---|---|---|
| Tissue | p[A]50 | nH | p[A]50 | nH |
| Uterus | 7.99±0.11 | 1.12±0.24 | 7.83±0.08 | 1.51±0.39 |
| Stomach – fundus | 8.15±0.14 | 1.11±0.73 | 8.15±0.13 | 1.01±0.31 |
| Stomach – corpus | 8.39±0.17 | 1.05±0.36 | NR | |
| LES | 7.59±0.35 | 1.07±0.77 | ND | |
| Ileum – longitudinal | 6.40±0.18 | 1.04±0.38 | NR | |
| Gallbladder | 8.05±0.27 | 0.93±0.40 | ||
| Vas deferens | ND | 7.97±0.32 | 0.96±0.53 | |
NR=no response, ND=dose–response curve not defined, but response observed.
The mid-point location (p[A]50±s.e.m.) and slope (nH±s.e.m.) of the curves are given where possible.