Table 1.

NOS and arginase substrates and inhibitors tested for activity at h6A/5.24

NOS substratesa

L-Arginine (natural substrate), L-homoarginine, L-NOHA, L-canavanineb

NOS inhibitorsc

ADMA, aminoguanidine, L-NG-aminoarginine, L-canavanine, L-NAME, L-NMMA, L-NMMHA, L-NOARG, L-NG-propylarginine, L-NIL, L-NIO, vinyl-L-NIO, L-thiocitrulline

Arginase substratesd

Agmatine, L-arginine (natural substrate), L-canavanine, L-homoarginine

Arginase inhibitorsd

L-NOARGe, L-NOHA, L-nor-NOHA

^aTaken from Luzzi & Marletta (2005) and Southan & Szabó (1996).

^bReported as a weak NOS substrate (Yokoi et al., 1994).

^cTaken from Proskuryakov et al. (2005) and Southan & Szabó (1996).

^dTaken from Christianson (2005).

^eReported as rat liver arginase inhibitor Robertson et al. (1993).