Table 1.
Effects of diabetes and AG on blood glucose level, body weight, left ventricular weight, and aortic pressure profile in male Wistar rats
| Variable | NC (n=17) | NC+AG (n=17) | DM (n=17) | DM+AG (n=17) |
|---|---|---|---|---|
| Glucose (ml dl−1) | 102.4±2.8 | 95.7±2.2 | 437.1±13.6† | 428.9±14.9 |
| BW (g) | 447.7±6.8 | 437.9±7.0 | 280.5±10.0† | 283.0±8.6 |
| LVW (g) | 0.853±0.017 | 0.839±0.018 | 0.722±0.027† | 0.590±0.023‡ |
| LVW/BW (mg g−1) | 1.91±0.03 | 1.92±0.03 | 2.58±0.06† | 2.08±0.04‡ |
| Ps (mmHg) | 120.6±2.0 | 124.5±2.2 | 112.3±2.4 | 108.0±2.6 |
| Pd (mmHg) | 95.6±1.7 | 98.2±2.4 | 86.2±2.5 | 83.4±2.7 |
| Pm (mmHg) | 109.1±1.7 | 112.5±2.3 | 100.0±2.3 | 97.4±2.6 |
| PP (mmHg) | 25.0±1.5 | 26.6±0.9 | 26.2±1.1 | 24.6±1.2 |
All values are expressed as means±s.e. BW, body weight; LVW, left ventricular weight; Ps, systolic aortic pressure; Pd, diastolic aortic pressure; Pm, mean aortic pressure; PP, pulse pressure.
†
Statistical difference (P<0.05) from the control group (NC).
‡
Statistical difference (P<0.05) from the STZ-diabetic group (DM). AG, aminoguanidine.