Figure 2.
The release of substances from the guinea-pig lung induced by anaphylactic shock. The tissues, including the cat terminal ileum (CTI), the rabbit aortic strip (Rba), the chick rectum (CR), the guinea-pig trachea (GPT), the rat stomach strip (RSS) and the rat colon (RC), were superfused with effluent from a sensitised guinea-pig perfused lung in preparation. Egg albumin (EA) was injected through the lungs (i.a.) and caused a massive release of a substance, which could not be accounted for by the presence of histamine or PGE2, which were also tested directly (DIR) over the tissues. From Vane (1971b), with permission.