Skip to main content
. 2006 Jan 9;147(Suppl 1):S212–S221. doi: 10.1038/sj.bjp.0706475

Table 1. Human chemokines identified to date.

Systematic name Colloquial name Receptor usage Systematic name Colloquial name Receptor usage
CCL1 I-309 CCR8 CXCL1 GROα/MGSA-α CXCR2
CCL2 MCP-1/MCAF CCR2 CXCL2 GROβ/MGSA-β CXCR2
CCL3 MIP-1α/LD78α CCR1, 5 CXCL3 GROγ/MGSA-γ CXCR2
CCL3L1 LD78β CCR1, 5 CXCL4 PF-4 CXCR3B
CCL4 MIP-1β CCR5 CXCL5 ENA-78 CXCR2
CCL4L1 LAG-1 CCR5 CXCL6 GCP-2 CXCR1, 2
CCL5 RANTES CCR1, 3, 5 CXCL7 NAP-2 CXCR2
CCL7 MCP-3 CCR1, 2, 3 (CCR5) CXCL8 IL-8 CXCR1, 2
CCL8 MCP-2 CCR3 CXCL9 Mig CXCR3 (CCR3)
CCL11 Eotaxin CCR3 (CCR2) CXCL10 IP-10 CXCR3 (CCR3)
CCL13 MCP-4 CCR2, 3 CXCL11 I-TAC CXCR3 (CCR3)
CCL14 HCC-1 CCR1 CXCL12 SDF-1α/β CXCR4
CCL15 HCC-2/Lkn-1/MIP-1δ/MIP5 CCR1, 3 CXCL13 BLC/BCA-1 CXCR5
CCL16 HCC-4/LEC CCR1 CXCL14 BRAK/Bolekine  
CCL17 TARC CCR4 CXCL16 SR-PSOX CXCR6
CCL18 DC-CK-1/AMAC-1/MIP5/ PARC/MIP-4 CCR3      
CCL19 MIP-3β/ELC/Exodus-3 CCR7 XCL1 Lymphotactin/ SCM-1α/ATAC XCR1
CCL20 MIP3α/LARC/Exodus-1 CCR6 XCL2 SCM-1β XCR1
CCL21 SLC/6Ckine/Exodus-2 CCR7      
CCL22 MDC/STCP-1 CCR4 CX3CL1 Fractalkine, neurotactin CX3CR1
CCL23 MPIF-1 CCR1      
CCL24 MPIF-2/Eotaxin-2 CCR3      
CCL25 TECK CCR9      
CCL26 Eotaxin-3 CCR3, (CCR1, 2, 5)      
CCL27 CTACK/ALP/ILC/ESkine CCR10      
CCL28 MEC CCR10, 3      

The systematic names together with the colloquial names and receptor agonist activity are shown. Antagonist activity at other chemokine receptors is shown within parenthesis. Some human chemokines appear to be missing from the list, for example, CCL6. In such instances, while a chemokine of that name has been identified in the mouse, no human orthologue has been documented.

6ckine=chemokine with 6 cysteines; ALP=amino-terminal alanine-leucine-proline chemokine; AMAC=alternative macrophage activation-associated CC chemokine; ATAC=activation-induced, chemokine-related molecule; BCA=B-cell-attracting chemokine; BRAK=breast- and kidney-expressed chemokine; CTACK; cutaneous T-cell-activating chemokine; DARC=Duffy antigen receptor for chemokines; DC-CK1=dendritic cell-derived CC chemokine; ELC=EBL-1 ligand chemokine; ENA-78=epithelial neutrophil activating peptide 78; ESkine=embryonal stem cell chemokine; GCP=granulocyte chemotactic protein; GRO=growth-regulated oncogene; HCC=human CC chemokine; ILC=IL-11 receptor α-locus chemokine; IP, IFNγ-inducible protein; I-TAC=IFNγ-inducible T-cell chemoattractant; LAG=lymphocyte activation gene-1; LARC=liver- and activation-regulated chemokine; LEC=liver-expressed chemokine; Lkn=leukotactin; MCP=monocyte chemoattractant protein; MCAF=monocyte chemotactic and activating factor; MDC=monocyte-derived chemokine; MEC=mucosae-associated epithelial chemokine; MGSA=melanoma growth stimulatory activity; Mig=monokine-induced by IFNγ; MIP=macrophage inflammatory protein; MPIF=myeloid progenitor inhibitory factor; NAP=neutrophil-activating peptide; PARC=pulmonary- and activation-regulated chemokine; PF=platelet factor; RANTES=regulated on activation, normal T-cells expressed and secreted; SCM=single C motif; SDF-1=stromal cell-derived factor 1; SLC=secondary lymphoid tissue chemokine; SR-PSOX=scavenger receptor for phosphatidylserine and oxidized lipoprotein; STCP=stimulated T-cell chemoattractant protein; TARC=thymus- and activation-regulated chemokine; TECK=thymus-expressed chemokine.

HHS Vulnerability Disclosure