Figure 1. Representative Germline CNVs in Mice Identified by High-Resolution aCGH.
The log2 ratios of signal intensity for C57BL/6J (reference) versus 20 test strains are shown. Inset, an expanded view of the CNVs in NOD/LtJ and A/J from (A) and (B). Scale, 500 kb.
(A) A 135.6-kb segment of reduced copy number (mean log2 = −1.02) on Chromosome 14 is present in most strains.
(B) A 61.7-kb amplified segment (mean log2 = +1.01) on Chromosome 1 is present in most strains.