Table 1.
Demographic and Clinical Correlates of ICDs
| Variable | No Active ICDa(N=261) | Active ICD (N=11) | Pvalue |
|---|---|---|---|
| Age, years | 68.6 (10.2) | 59.5 (9.4) | .006b* |
| Male, N (%) | 182 (69.7) | 10 (90.9) | .184c |
| Married, N (%) | 206 (79.2) | 9 (81.8) | >.999c |
| Education, years | 14.7 (3.0) | 14.7 (3.1) | .981b |
| PD duration, years | 6.9 (5.8) | 11.2 (7.5) | .039b* |
| Levodopa dosage, mg/day | 448.1 (335.2) | 543.6 (453.5) | .493b |
| Total LEDDd, mg/day | 569.3 (369.1) | 925.5 (534.9) | .037b* |
| Dopamine agonist use, N (%) | 126 (48.3) | 11 (100.0) | <.001c* |
| Amantadine use, N (%) | 49 (18.8) | 6 (54.5) | .011c* |
| MMSE score | 28.3 (2.0) | 28.6 (1.4) | .964b |
| GDS score | 4.0 (3.8) | 6.0 (5.5) | .262b |
| ICD behavior prior to PD, N (%) | 9 (3.5) | 4 (36.4) | <.001c* |
Note: Values are mean (±standard deviation) unless otherwise indicated.
a
Includes patients who once had an ICD, either prior to onset of or sometime during the course of PD
b
Wilcoxon two-sample test
c
Fisher’s exact test
d
Levodopa equivalent daily dose for dopamine agonists + levodopa from other medications
*
P value ≤.05