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. Author manuscript; available in PMC: 2007 Dec 13.
Published in final edited form as: Brain Res. 2006 Nov 16;1125(1):46–59. doi: 10.1016/j.brainres.2006.09.090

Table 5.

Responses to activation of cardiopulmonary reflexes (i.v. phenylbiguanide, PBG) and central baroreflex pathways (microinjection of NTS l-glu) (Protocol 3)

Control After RVLM GX+S
Δ MAP (mm Hg) Δ RSNA (% i/sec) Δ RSNA (% RMS) Δ MAP (mm Hg) Δ RSNA (% i/sec) Δ RSNA (% RMS)
PBG −33.9 ± 7.2 −59.3 ± 10.1 −82.8 ± 4.4 −2.7 ± 4.0* 4.6 ± 5.3* 5.1± 4.2*
NTS l-glu −35 ± 4.0 −51.9 ± 10.9 −74.4± 6.9 0.4 ± 3.9* 6.5 ± 3.3* −6.9 ± 3.5*

At the beginning of the protocol (Control), both PBG and unilateral microinjection of l-glu into the NTS resulted in significant decreases in MAP and RSNA. Bilateral blockade of GABAA, GABAB, and glycine receptors (GX + S) in the RVLM eliminated reflex responses. Values = mean ± SEM;

*

P ≤ 0.05 compared to corresponding control value.