Skip to main content
. Author manuscript; available in PMC: 2007 Jan 3.
Published in final edited form as: Chem Commun (Camb). 2006 Jul 21;(27):2884–2886. doi: 10.1039/b604329a

Scheme 2.

Scheme 2

Initial planar support derivatization. Reagents and conditions: (i) N,N′-diisopropylcarbodiimide (DIC), N-hydroxysuccinimide (HOSu), diisopropylethylamine (DIPEA), NMP, MW 95 °C, 8 min. (ii) Capping step: Ac2O, DIPEA, DMF, rt, 20 min (2×).17 (iii) 20% piperidine in DMF, rt, 10 min (2×). (iv) DIC, HOSu, DIPEA, NMP, MW 100 °C, 10 min.