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Expression of MyoXVIIIAβ/SP-R210S in COS-1 cells confers SP-A binding. Binding of SP-A to control and MyoXVIIIAβ/SP-R210S-expressing cells was determined using 125 I-labeled SP-A. The saturation isotherm and Scatchard analysis of binding data (inset) show 2.5-fold increase in SP-A binding to MyoXVIIIAβ/SP-R210S-expressing cells.
