Table 2.

Allele frequency and genotype distribution of I/D polymorphism at ACE locus in TCP patients & control subjects

	Patients			Controls	P Value
	TCP	FCPD	Total		TCP vs. FCPD	TCP vs. controls	FCPD vs. controls
n	91	80	171	99	-	-	-
Allele frequency
I	0.56	0.52	0.54	0.53	0.57	0.67	0.89
D	0.44	0.48	0.46	0.47
Genotype frequency based on the presence or absence of the mutant allele
II	0.33 (30)	0.24 (19)	0.29 (49)	0.26 (26)	0.16	0.28	0.74
ID + DD	0.67 (61)	0.76 (61)	0.71 (122)	0.74 (73)

n, number of individuals; TCP, tropical calcific pancreatitis; FCPD, fibro-calculous pancreatic diabetes; ACE, angiotensin converting enzyme; I/D, insertion/deletion polymorphism at ACE locus figures in parentheses indicate number of individuals; P values are represented on comparison of TCP with FCPD, TCP with controls and FCPD with controls.