Table 3.
Clinical features of TCP and FCPD patients grouped according to their genotype at in/del polymorphism at ACE gene
| TCP | FCPD | Total | |||||||
| II | ID/DD | P value | II | ID/DD | P value | II | ID/DD | P value | |
| n | 30 | 61 | - | 19 | 61 | - | 49 | 122 | - |
| Sex (Male/Female) | 22/8 | 39/22 | - | 17/2 | 42/19 | - | 39/10 | 81/41 | - |
| Age at onset (yrs) | 25.7 ± 11.1 | 24.8 ± 11.8 | 0.72 | 34.4 ± 15.1 | 31.2 ± 12.9 | 0.37 | 29.0 ± 13.3 | 28.0 ± 12.7 | 0.64 |
| Age at presentation (yrs) | 36.2 ± 11.8 | 32.7 ± 10.9 | 0.16 | 40.3 ± 17.0 | 38.9 ± 13.9 | 0.72 | 37.8 ± 14.0 | 35.8 ± 12.9 | 0.37 |
| Age at onset of diabetes (yrs) | NA | NA | NA | 34.2 ± 13.9 | 33.7 ± 11.44 | 0.88 | 34.2 ± 13.9 | 33.7 ± 11.4 | 0.81 |
| Pancreatic surgery | 11 (36.67%) | 24 (40%) | 0.76 | 2 (10.53%) | 4 (6.56%) | 0.57 | 13 (26.53%) | 28 (23.14%) | 0.64 |
| Calcification | 30 (100%) | 61 (100%) | 1 | 19 (100) | 61 (100) | 1 | 49 (100) | 122 (100) | 1 |
| Pseudocyst | 2 (6.67%) | 4 (6.6%) | 1 | 0 (0%) | 1 (1.64) | 1 | 2 (4.08%) | 5 (4.13%) | 1 |
n, number of individuals; TCP, tropical calcific pancreatitis; FCPD, fibro-calculous pancreatic diabetes; ACE, angiotensin converting enzyme
I/D, insertion/deletion polymorphism at ACE locus; NA, not applicable; figures in parentheses indicate percentage; figures are quoted as mean ± SD
P values are represented on comparison of II vs ID+DD genotypes in TCP, FCPD and total patients