Table 12.
Significant biological functions for MIN-O vs PL expression differences for 8w-D line
Name | GO ID | Corrected P-value |
Response to radiation/UV | ||
phototransduction | GO:0007602 | 0.00E+00 |
detection of light | GO:0009583 | 0.00E+00 |
response to radiation | GO:0009314 | 0.00E+00 |
response to light | GO:0009416 | 0.00E+00 |
response to UV | GO:0009411 | 2.88E-02 |
Apoptosis | ||
apoptotic program | GO:0008632 | 0.00E+00 |
Immune response | ||
complement activation, classical pathway | GO:0006958 | 9.56E-03 |
positive regulation of immune response | GO:0050778 | 1.15E-02 |
regulation of immune response | GO:0050776 | 1.36E-02 |
T-cell activation | GO:0042110 | 2.23E-02 |
antigen processing | GO:0030333 | 2.25E-02 |
cellular defense response (sensu Vertebrata) | GO:0016066 | 2.32E-02 |
antimicrobial humoral response | GO:0019730 | 2.58E-02 |
positive regulation of lymphocyte activation | GO:0051251 | 2.60E-02 |
xenobiotic metabolism | GO:0006805 | 2.58E-02 |
symbiotic interaction between host and other organism | GO:0044404 | 2.56E-02 |
oxygen and reactive oxygen species metabolism | GO:0006800 | 3.21E-02 |
complement activation | GO:0006956 | 3.21E-02 |
response to xenobiotic stimulus | GO:0009410 | 3.97E-02 |
lymphocyte differentiation | GO:0030098 | 3.94E-02 |
pathogenesis | GO:0009405 | 3.96E-02 |
T-helper 1 type immune response | GO:0042088 | 4.19E-02 |
detection of biotic stimulus | GO:0009595 | 4.49E-02 |
cytokine and chemokine mediated signaling pathway | GO:0019221 | 4.72E-02 |
antigen presentation, endogenous antigen | GO:0019883 | 4.71E-02 |
lymphocyte proliferation | GO:0046651 | 4.90E-02 |
antigen presentation | GO:0019882 | 8.19E-03 |
Angiogenesis | ||
blood vessel morphogenesis | GO:0048514 | 8.92E-03 |
blood vessel development | GO:0001568 | 1.17E-02 |
angiogenesis | GO:0001525 | 1.47E-02 |
ECM | ||
extracellular structure organization and biogenesis | GO:0043062 | 3.18E-02 |
extracellular matrix organization and biogenesis | GO:0030198 | 3.15E-02 |
cell-matrix adhesion | GO:0007160 | 4.31E-02 |
Signaling pathways | ||
I-kappaB kinase/NF-kappaB cascade | GO:0007249 | 0.00E+00 |
regulation of I-kappaB kinase/NF-kappaB cascade | GO:0043122 | 2.38E-02 |
positive regulation of I-kappaB kinase/NF-kappaB cascade | GO:0043123 | 2.35E-02 |
Wnt receptor signaling pathway | GO:0016055 | 1.16E-04 |
Ras protein signal transduction | GO:0007265 | 4.61E-03 |
inactivation of MAPK | GO:0000188 | 2.43E-02 |
Steroid | ||
steroid biosynthesis | GO:0006694 | 3.27E-06 |
sterol metabolism | GO:0016125 | 4.16E-02 |