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. 2006 Dec 5;7:529. doi: 10.1186/1471-2105-7-529

Figure 2.

Figure 2

Scatter plots comparing the variance estimators. The upper-left plot shows the strong agreement between σ2(Δ^triplet) and our approximation σ2(Δ^pairwise). From the upper-right and the lower-left plots, it can be seen that both have similar correlation with σbootstrap2(Δ^pairwise). Finally, the lower-right plot confirms that variance estimation under the assumption of independence can yield a large overestimation of the correct variance.