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. 2002 May;136(1):49–56. doi: 10.1038/sj.bjp.0704693

Figure 7.

Figure 7

Effect of SNP on Ca2+ mobilization in isolated pancreatic acinar cells. (A) Original recordings showing the effect of ACh (1×10−5 M) on intracellular free Ca2+ concentration ([Ca2+]i) in a suspension of fura-2 loaded pancreatic acinar cells in the absence (upper panel) and presence of SNP (1×10−3 M, lower panel). The arrows indicate the addition of the drugs. Traces are typical of 8 – 10 such experiments. (B) Bar charts showing [Ca2+]i during basal condition and following the addition of ACh (1×10−5 M), SNP (1×10−3 M) or ACh (1×10−5 M) in the presence of SNP. Measurements were made at the peak (20 – 25 s) of the response. Each point is mean±s.e.mean (n=8 – 10).