Figure 2. Electrolytic ablation of the PVH: histological verification and effects on autonomic thermoregulation.

(A) Serial coronal brain sections are shown for a sham-lesioned rat and a PVH-lesioned rat. Arc, arcuate hypothalamic nucleus; ME, median eminence; mt, mammillothalamic tract; sox, supraoptic decussation; VMH, ventromedial hypothalamic nucleus.

Other abbreviations used are the same as in Figure 1.

(B) The ability of sham-lesioned and PVH-lesioned rats to defend their T_b by autonomic mechanisms during moderate heat exposure (28°C, 2 h) or mild cold exposure (17°C, 2 h).