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. 2006 Dec 20;1(1):e57. doi: 10.1371/journal.pone.0000057

Table 2. Transcripts with decreased expression in spleens of T. cruzi- infected susceptible B6 mice with respect to resistant F1 mice.

graphic file with name pone.0000057.t002.jpg

Gene Symbola Gene Title (Annotations) Mean SLRb Affymetrix Probe ID
Igh-1a immunoglobulin heavy chain 1a (serum IgG2a) −7.9 1451632_a_at
H2-Ea histocompatibility 2, class II antigen E alpha −7.9 1422892_s_at
H2-D1 histocompatibility 2, D region locus 1 −7.6 1452544_x_at
H2-D1 histocompatibility 2, D region locus 1 −7.4 1425614_x_at
Ifi202b interferon activated gene 202B −7.1 1421551_s_at
H2-Ea histocompatibility 2, class II antigen E alpha −6.2 1422891_at
H2-D1 histocompatibility 2, D region locus 1 −6.2 1427651_x_at
Mela melanoma antigen −4.3 1456182_x_at
H2-Q1 Histocompatibility 2, D region locus 1 −3.6 1451593_at
Mcpt2 mast cell protease 2 −3.6 1449989_at
2210010A19Rik Riken cDNA 2210010A19 gene (hypoth. pyridoxal-dependent decarboxylase family containing protein) −3.3 1419327_at
Ng23 Ng23 protein −3.1 1422952_at
Tnfrsf14/HVEM tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) −2.8 1452425_at
Gm288 Gene model 288, (NCBI) −2.8 1435998_at
Pnpt1 polyribonucleotide nucleotidyltransferase 1 −2.5 1452677_at
Serpina1b/Serpina1d/Serpina1e serine (or cysteine) proteinase inhibitor, clade A, member 1b/serine (or cysteine) proteinase inhibitor, clade A, member 1d/serine (or cysteine) proteinase inhibitor, clade A, member 1e −2.4 1418282_x_at
Wdtc1 WD and tetratricopeptide repeats 1 −2.2 1434560_at
Sfi1/LOC673420 Sfi1 homolog, spindle assembly associated (yeast)/similar to spindle assembly associated Sfi1 homolog isoform b −2.1 1452195_s_at
Msh5 mutS homolog 5 (E. coli) −1.9 1430771_a_at
Gcg glucagon −1.7 1425952_a_at
LOC628926 hypothotetical protein LOC628926 −1.7 1427553_at
Dnase1l3 deoxyribonuclease 1-like 3 −1.6 1421056_at
Cxcl11 chemokine (C-X-C motif) ligand 11 −1.6 1419697_at
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) −1.5 1417461_at
Aps adaptor protein with pleckstrin homology and src −1.4 1450718_at
Bmp2k BMP2 inducible kinase −1.4 1421103_at
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) −1.3 1417462_at
AI324046 expressed sequence AI324046 (immunoglobulin heavy chain, IgG3) −1.2 1447998_at
Foxj3 forkhead box J3 −1.1 1438220_at
Ptp4a2 Protein tyrosine phosphatase 4a2 −1.0 1435129_at
Ets1 E26 avian leukemia oncogene 1, 5′ domain −1.0 1422028_a_at
D13Ertd608e DNA segment, chr 13, ERATO Doi 608, expressed −1.0 1439771_s_at
Srd5a2l steroid 5 alpha-reductase 2-like −1.0 1439241_x_at
Supt16h suppressor of Ty 16 homolog (S. cerevisiae) −1.0 1449578_at
E030041M21Rik RIKEN cDNA E030041M21 gene −0.9 1451276_at
37135 septin 1 −0.9 1449898_at
Hyou1 hypoxia up-regulated 1 −0.9 1423290_at
Rnf6 ring finger protein (C3H2C3 type) 6 −0.8 1427899_at
Alad aminolevulinate, delta-, dehydratase −0.8 1424877_a_at
Tubb5 tubulin, beta 5 −0.8 1455719_at
Rbm5 RNA binding motif protein 5 −0.8 1456262_at
Comt catechol-O-methyltransferase −0.8 1418701_at

Affymetrix GeneChip Mouse Expression Array 430A

a

Bold gene title: Differential expression verified in an independent analysis, see text

b

Mean SLR: Signal log ratio, log2