Table 2. Transcripts with decreased expression in spleens of T. cruzi- infected susceptible B6 mice with respect to resistant F1 mice.
Gene Symbola | Gene Title (Annotations) | Mean SLRb | Affymetrix Probe ID |
Igh-1a | immunoglobulin heavy chain 1a (serum IgG2a) | −7.9 | 1451632_a_at |
H2-Ea | histocompatibility 2, class II antigen E alpha | −7.9 | 1422892_s_at |
H2-D1 | histocompatibility 2, D region locus 1 | −7.6 | 1452544_x_at |
H2-D1 | histocompatibility 2, D region locus 1 | −7.4 | 1425614_x_at |
Ifi202b | interferon activated gene 202B | −7.1 | 1421551_s_at |
H2-Ea | histocompatibility 2, class II antigen E alpha | −6.2 | 1422891_at |
H2-D1 | histocompatibility 2, D region locus 1 | −6.2 | 1427651_x_at |
Mela | melanoma antigen | −4.3 | 1456182_x_at |
H2-Q1 | Histocompatibility 2, D region locus 1 | −3.6 | 1451593_at |
Mcpt2 | mast cell protease 2 | −3.6 | 1449989_at |
2210010A19Rik | Riken cDNA 2210010A19 gene (hypoth. pyridoxal-dependent decarboxylase family containing protein) | −3.3 | 1419327_at |
Ng23 | Ng23 protein | −3.1 | 1422952_at |
Tnfrsf14/HVEM | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) | −2.8 | 1452425_at |
Gm288 | Gene model 288, (NCBI) | −2.8 | 1435998_at |
Pnpt1 | polyribonucleotide nucleotidyltransferase 1 | −2.5 | 1452677_at |
Serpina1b/Serpina1d/Serpina1e | serine (or cysteine) proteinase inhibitor, clade A, member 1b/serine (or cysteine) proteinase inhibitor, clade A, member 1d/serine (or cysteine) proteinase inhibitor, clade A, member 1e | −2.4 | 1418282_x_at |
Wdtc1 | WD and tetratricopeptide repeats 1 | −2.2 | 1434560_at |
Sfi1/LOC673420 | Sfi1 homolog, spindle assembly associated (yeast)/similar to spindle assembly associated Sfi1 homolog isoform b | −2.1 | 1452195_s_at |
Msh5 | mutS homolog 5 (E. coli) | −1.9 | 1430771_a_at |
Gcg | glucagon | −1.7 | 1425952_a_at |
LOC628926 | hypothotetical protein LOC628926 | −1.7 | 1427553_at |
Dnase1l3 | deoxyribonuclease 1-like 3 | −1.6 | 1421056_at |
Cxcl11 | chemokine (C-X-C motif) ligand 11 | −1.6 | 1419697_at |
Cap1 | CAP, adenylate cyclase-associated protein 1 (yeast) | −1.5 | 1417461_at |
Aps | adaptor protein with pleckstrin homology and src | −1.4 | 1450718_at |
Bmp2k | BMP2 inducible kinase | −1.4 | 1421103_at |
Cap1 | CAP, adenylate cyclase-associated protein 1 (yeast) | −1.3 | 1417462_at |
AI324046 | expressed sequence AI324046 (immunoglobulin heavy chain, IgG3) | −1.2 | 1447998_at |
Foxj3 | forkhead box J3 | −1.1 | 1438220_at |
Ptp4a2 | Protein tyrosine phosphatase 4a2 | −1.0 | 1435129_at |
Ets1 | E26 avian leukemia oncogene 1, 5′ domain | −1.0 | 1422028_a_at |
D13Ertd608e | DNA segment, chr 13, ERATO Doi 608, expressed | −1.0 | 1439771_s_at |
Srd5a2l | steroid 5 alpha-reductase 2-like | −1.0 | 1439241_x_at |
Supt16h | suppressor of Ty 16 homolog (S. cerevisiae) | −1.0 | 1449578_at |
E030041M21Rik | RIKEN cDNA E030041M21 gene | −0.9 | 1451276_at |
37135 | septin 1 | −0.9 | 1449898_at |
Hyou1 | hypoxia up-regulated 1 | −0.9 | 1423290_at |
Rnf6 | ring finger protein (C3H2C3 type) 6 | −0.8 | 1427899_at |
Alad | aminolevulinate, delta-, dehydratase | −0.8 | 1424877_a_at |
Tubb5 | tubulin, beta 5 | −0.8 | 1455719_at |
Rbm5 | RNA binding motif protein 5 | −0.8 | 1456262_at |
Comt | catechol-O-methyltransferase | −0.8 | 1418701_at |
Affymetrix GeneChip Mouse Expression Array 430A
Bold gene title: Differential expression verified in an independent analysis, see text
Mean SLR: Signal log ratio, log2