Table 1. Effect of neuroprotection on Alzheimer's disease (AD).

	Baseline	Protect-1		Protect-2
Age (yrs)	AD cases	AD cases	%	AD cases	%
65–69	1,640	482	71	753	54
70–74	3,353	1,140	66	1,653	51
75–79	6,501	2,595	60	3,488	46
80–84	11,600	5,569	52	6,936	40
85–89	16,337	9,548	42	11,119	32
90–94	16,222	11,450	29	12,689	22
Total	55,652	30,785	45	36,638	34

Baseline values are the expected number of cases of Alzheimer's disease (AD) at any given age (from an original at risk population of 100,000). These values were obtained from the loess curve of basic cognitive units (see Fig. 2). Neuroprotection obtained by 1) a 5% increase in the number of basic cognitive units at any given age (Protect-1), and 2) a 5% increase in the cognitive reserve (Protect-2).