Table 4. HCMp's In Model Organisms And Selected Parasite Genomes.
Organism | Genome Size (Mbp) | ≥10% Cysteine (>400 aa) | Type1 TM (>400 aa) | HCMp's | % Genome* |
G. lamblia a | 12 | 173 | 152 | 61 | 0.63 |
T. thermophila b | 104 | 285 | 45 | 30 | 0.11 |
H. sapiens c | 2,910 | 28 | 9 | 7 | 0.025 |
E. histolytica d | 20 | 28 | 17 | 6 | 0.06 |
D. melanogaster e | 180 | 18 | 6 | 4 | 0.03 |
C. elegans f | 97 | 39 | 9 | 4 | 0.02 |
A. thaliana | 125 | 6 | 4 | 0 | |
T. gondii | 80 | 7 | 3 | 0 | |
C. rheinhardtii | 120 | 3 | 1 | 0 | |
T. brucei | 30 | 3 | 1 | 0 | |
P. falciparum | 23 | 0 | 0 | 0 | |
S. cerevisiae | 12 | 0 | 0 | 0 | |
C. parvum | 10 | 0 | 0 | 0 |
G. lamblia : Giardia genome ORF numbers from GiardiaDB (www.mbl.edu/Giardia):
40376,11309,25816,32607,10659,16318,15317,103454,101805,91707,7715,15008,17328,22547,9620,14017,15475,39904,16721,16842,15521,16374,91099,24880,27717,112126,113987,114891,114042,114089,112828,114930,114617,112633,137727,113213,113836,113531,114626,114991,16936,16716,21321,137715,112432,15250,41942,113512,114470,114180,113319,113416,112673,112135,115066,112584,113297,113801,137672,112305,11852
T. thermophila : gi|89285635,gi|89286821,gi|89288525,gi|89288637,gi|89288695,gi|89289016,gi|89289736,gi|89290140,gi|89290464,gi|89291419,gi|89291425,gi|89292518,gi|89292756,gi|89293702,gi|89295361,gi|89295485,gi|89295487,gi|89295488,gi|89295496,gi|89295499,gi|89295601,gi|89296595,gi|89299183,gi|89300019,gi|89302034, gi|89302083,gi|89304603,gi|89304693,gi|89306011,gi|89306012
H. sapiens : gi|21704279,gi|21704277,gi|14192943,gi|14192941,gi|5453766,gi|10092639,gi|4503667
E. histolytica : gi|67476461,gi|67473447,gi|67476571,gi|67467895,gi|67476995,gi|67464660
D. melanogaster : CG33196,CG6124,CG2086,CG15011 from FlyBase (http://flybase.org/)
C. elegans : gi|25143262,gi|25150348,gi|25150352,gi|25150359
% Genome defined as number of HCMp's/predicted ORFs.