Table 1.
Peripheral Quantitative Computed Tomography Data in the Various Genotypes
| Variable | Control | Fgf-23−/− | Fgf-23−/−/1α(OH)ase−/− | 1α(OH)ase−/− |
|---|---|---|---|---|
| Femoral metaphysis | ||||
| Total BMD (mg/cm3) | 384.9 ± 26.4 | 290.0 ± 25.2 | 187.7 ± 0.9 | 182.7 ± 4.66 |
| Cortical/subcortical BMD (mg/cm3) | 621.7 ± 18.4 | 435.3 ± 76 | 333.7 ± 40.1 | 417.8 ± 41.4 |
| Trabecular BMD (mg/cm3) | 215.9 ± 33.5 | 200.4 ± 1.1 | 101.7 ± 17.2 | 81.5 ± 6.9 |
| Femoral shaft | ||||
| Total BMD (mg/cm3) | 462.8 ± 18.5 | 359.6 ± 22.4 | 230.2 ± 12.8 | 282 ± 20.7 |
| Total area (cm2) | 1.73 ± 0.05 | 1.28 ± 0.03 | 1.17 ± 0.23 | 1.09 ± 0.07 |
| Cortical area (cm2) | 0.658 ± 0.027 | 0.36 ± 0.06 | 0.125 ± 0.035 | 0.163 ± 0.04 |
| Cortical thickness (mm) | 0.158 ± 0.005 | 0.098 ± 0.02 | 0.035 ± 0.014 | 0.046 ± 0.011 |