Table 1.

Spirochetemia at Necropsy in Groups of Four Igh6^−/− Mice Each Uninfected (PBS) or Infected with B. turicatae Serotypes 1 (Bt1) or 2 (Bt2) and Treated with Either rIL-10 in Different Schedules or PBS as a Control

Group	Infection	Treatment	Spirochetes/ml plasma, median (range)
I	PBS	PBS	0
II	Bt2	PBS	8 × 107 (6.5 × 107 to 1.7 × 108)
III	Bt2	rIL-10 at 50 μg/kg on days 0 to 8	1.5 × 108 (7.5 × 107 to 1.5 × 108)
IV	Bt1	PBS	2 × 107 (1.5 × 107 to 2.5 × 107)*
V	Bt1	rIL-10 at 150 μg/kg on day 13	2 × 106 (1 × 106 to 5.5 × 106)*
VI	Bt1	rIL-10 at 100 μg/kg on days 11 to 13	1 × 107 (1 × 107 to 2 × 107)

^*P < 0.05 for the difference between groups IV and V and V and VI (Mann-Whitney U-test).