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Complement depletion by CVF abolishes the development of urine abnormalities, and elevation of serum blood urea nitrogen and creatinine in Rag2−/− mice 13 days after they received 5 × 107 anti-MPO splenocytes (A–D). Bars represent the SD. *P < 0.05, **P < 0.01, #P < 0.001 compared with untreated Rag2−/− mice (ie, with no anti-MPO splenocytes and no CVF).
