Table 3.

Measurements of Hearts under Normal and Diseased Conditions*

Condition	No. of rats examined	Diameter (mm)		Estimated area of hearts (mm2)†
		Long axis	Short axis
Normal	3	0.83 ± 0.10	0.72 ± 0.12	0.47 ± 0.14‡
CC2	6	1.20 ± 0.19	0.97 ± 0.08	0.91 ± 0.19‡
CC2P12	6	0.91 ± 0.08	0.80 ± 0.11	0.58 ± 0.13‡

^*Rats were immunized once with CC2 or CC2P12, and the hearts were taken at 6 weeks after immunization. The long and short axes of the diameter were measured at the middle portion of the hearts. The hearts from CC2P12-immunized rats were measured before and after fixation, and those from normal and CC2-immunized rats were measured only after fixation. Because there was no significant change before and after fixation, all the values shown in the table are those measured after fixation. 

^†The heart area was calculated as long axis/2 × short axis × 3.14. 

^‡Significant differences were noted between normal and CC2-immunized rats (P = 0.01) and between CC2- and CC2P12-immunized rats (P = 0.005). However, there was no significant difference between normal and CC2P12-immunized rats.