Table 3.
Probability that n product codon blocks lie a single point mutation away from the precursor codon blocks, where codons that differ by a U and C in the third position are constrained to code for the same amino acid
| x | n | a | b | P(X ≥ x) | −2lnP | |
|---|---|---|---|---|---|---|
| Ser→Trp | 1 | 1 | 21 (24) | 20 (20) | 0.512 (0.545) | 1.34 (1.21) |
| Ser→Cys | 1 | 1 | 21 (24) | 20 (20) | 0.512 (0.545) | 1.34 (1.21) |
| Phe→Tyr | 1 | 1 | 8 (8) | 36 (39) | 0.182 (0.170) | 3.41 (3.54) |
| Thr→Ile | 2 | 2 | 18 (20) | 24 (25) | 0.178 (0.192) | 3.46 (3.30) |
| Gln→His | 1 | 1 | 11 (11) | 32 (35) | 0.256 (0.239) | 2.73 (2.86) |
| Glu→Gln | 2 | 2 | 11 (13) | 32 (33) | 0.0609 (0.0754) | 5.60 (5.17) |
| Asp→Asn | 1 | 1 | 8 (8) | 36 (39) | 0.182 (0.170) | 3.41 (3.54) |
| Asp→Met | 0 | 1 | 8 (8) | 36 (39) | 1.00 (1.00) | 0.00 (0.00) |
χ2 = 21.27 (20.84).