Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Chemical structures and relative ratios of double-strand to single-strand lesions generated. Three enediynes were used for treatment in S. cerevisiae including calicheamicin γ1I, esperamicin A1 and neocarzinostatin. Each of these results in varying ratios of double-strand (DS) to single-strand (SS) lesions in DNA as outlined in Table 1.
