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Hierarchical cluster and principal component analysis of damage-induced gene expression ratios. WT S. cerevisiae was exposed to damage induced by enediynes: calicheamicin γ1I (cal), esperamicin A1 (esp) and neocarzinostatin (ncs) or γ-radiation (gamma). Significantly modulated transcripts in any one experiment (see Methods) were identified resulting in 225 ORFs and clustered hierarchically (A) or analyzed for principal components (B).
