Table 2.

Gene expression changes in response to enediyne or γ-radiation treatment^a

	# of unique ORFS with ≥ 1.5-fold change b
	Increased Expression	Decreased Expression	Total
Calicheamicin γ 1 I	4	3	7
Esperamicin A1	5	13	18
Neocarzinostatin	26	37	63
γ-Radiation	77	74	151

^a WT S. cerevisiae was exposed to enediynes or γ-radiation and their relative transcriptomes compared. Total numbers of unique ORFs are represented that showed significant modulation (see Methods).

^b Adjusted p-value ≤ 0.1