Fig. 3.
Chronic ethanol feeding increased basal activity of PDE4. Adipocytes isolated from pair- and ethanol-fed rats were incubated with or without 1 μm isoproterenol for 5 min. Cell homogenates were used to analyze PDE activity as described in Materials and Methods. Data represent means ± sem (n = 8 for basal samples or 4 for isoproterenol-treated samples). Values with different letters are significantly different (P < 0.05). EtOH, Ethanol.