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. Author manuscript; available in PMC: 2007 Nov 10.
Published in final edited form as: J Control Release. 2006 Sep 22;116(1):83–89. doi: 10.1016/j.jconrel.2006.09.005

Fig. 1.

Fig. 1

QD-FRET nanocomplex formulation and physical characteristics. (a) pDNA and chitosan were labeled with 605QD and Cy5, respectively. Condensation of DNA and chitosan by complex coacervation formed QD-FRET nanocomplexes. Upon excitation at 488 nm, QD-FRET-mediated Cy5 emission (pseudo-colored green) indicates a compact and intact nanocomplex. (b) Size (circle) and zeta potential (triangle) of nanocomplexes were not altered by QD or Cy5 labeling. (c) TEM image of a typical nanocomplex with electron-dense QDs conjugated to multiple encapsulated plasmids.