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. Author manuscript; available in PMC: 2007 Nov 10.
Published in final edited form as: J Control Release. 2006 Sep 22;116(1):83–89. doi: 10.1016/j.jconrel.2006.09.005

Fig. 3.

Fig. 3

Fluorescent image analysis of single QD-FRET nanocomplexes. Fluorescence images of (a) 605QD-labeled pDNA, (b) nanocomplexes, and (c) disrupted nanocomplexes. 605QD and FRET-mediated Cy5 signals are pseudo-colored in red and green, respectively. Colocalization is displayed in yellow/orange and indicates the tight association of plasmid and polymer within intact QD-FRET nanocomplexes. After treatment with heparin and chitosanase, nanocomplexes were disrupted and no longer exhibited FRET or colocalized signals. Scale bar: 1 μm.