Table 2.
Risk factors for the development of severe sepsis after burn injury following adjustment for multiple factors.
Variable (n=228) | Odds Ratio | 95% CI Odds Ratio | P-value |
Age | 1.010 | 0.991–1.028 | 0.305 |
Full-thickness burn size | 1.025 | 1.011–1.040 | 0.001 |
Gender (female) | 1.726 | 0.813–3.662 | 0.155 |
Inhalation injury | 2.714 | 1.246–5.912 | 0.012 |
Race/ethnicity | 1.197 | 0.828–1.729 | 0.339 |
CD14 -159C | 1.668 | 1.007–2.763 | 0.047 |
IL-1β-31C | 1.272 | 0.593–2.726 | 0.537 |
IL-6 -174C | 2.250 | 1.037–4.884 | 0.040 |
TNF-α-308A | 2.602 | 1.229–5.512 | 0.013 |
TLR4 +896G | 2.943 | 1.131–7.660 | 0.027 |
Odds ratios were determined by multivariate logistic regression. Age and full thickness burn size were analyzed as continuous variables. The odds ratios listed are for each additional year of age or each 1% increase in burn size. Race/ethnicity included the same categories as in table 1 ▶: Caucasian (n=129), Hispanic (n=51), African-American (n=41) and other (n=7).