Table 2.
Relative risks (RRs) and 95% confidence intervals (CIs) for associations between intake of specific types of alcohol at various ages and risk of ovarian cancer
| Alcohol type | Time period | Daily intake (g/day) | Median (g/day) | Cases (n) | RRa | 95% CIa | RRb | 95% CIb |
|---|---|---|---|---|---|---|---|---|
| Total alcohol | ||||||||
| Year before baseline | ||||||||
| None | 0.0 | 77 | 1.00 | (reference) | — | |||
| <10.0 | 4.5 | 81 | 1.04 | (0.76, 1.42) | — | |||
| 10.0– < 20.0 | 11.8 | 72 | 1.47 | (1.06, 2.03) | — | |||
| ≥20.0 | 28.2 | 23 | 1.15 | (0.71, 1.84) | — | |||
| Ptrend = 0.19 | ||||||||
| Ages 30–35 yearsc | ||||||||
| None | 0.0 | 67 | 1.00 | (reference) | — | |||
| <10.0 | 7.3 | 101 | 1.14 | (0.83, 1.56) | — | |||
| 10.0– < 20.0 | 11.8 | 47 | 1.08 | (0.74, 1.59) | — | |||
| ≥20.0 | 29.7 | 16 | 0.99 | (0.56, 1.71) | — | |||
| Ptrend = 0.99 | ||||||||
| Ages 18–22 yearsd | ||||||||
| None | 0.0 | 131 | 1.00 | (reference) | — | |||
| <10.0 | 4.5 | 62 | 0.76 | (0.55, 1.03) | — | |||
| 10.0– < 20.0 | 11.8 | 36 | 1.26 | (0.86, 1.84) | — | |||
| ≥20.0 | 28.8 | 9 | 1.00 | (0.50, 1.99) | — | |||
| Ptrend = 0.63 | ||||||||
| Beer | ||||||||
| Year before baseline | ||||||||
| None | 0.0 | 199 | 1.00 | (reference) | 1.00 | (reference) | ||
| <13.2 | 4.0 | 51 | 0.96 | (0.70, 1.31) | 0.89 | (0.64, 1.24) | ||
| ≥13.2 | 13.2 | 3 | 0.58 | (0.19, 1.84) | 0.54 | (0.17, 1.70) | ||
| Ptrend = 0.40 | Ptrend = 0.22 | |||||||
| Ages 30–35 yearsc | ||||||||
| None | 0.0 | 180 | 1.00 | (reference) | 1.00 | (reference) | ||
| <13.2 | 4.0 | 45 | 0.81 | (0.58, 1.13) | 0.75 | (0.53, 1.06) | ||
| ≥13.2 | 13.2 | 6 | 0.72 | (0.32, 1.64) | 0.73 | (0.32, 1.69) | ||
| Ptrend = 0.20 | Ptrend = 0.16 | |||||||
| Ages 18–22 yearsd | ||||||||
| None | 0.0 | 179 | 1.00 | (reference) | 1.00 | (reference) | ||
| <13.2 | 4.0 | 46 | 0.95 | (0.68, 1.32) | 0.93 | (0.65, 1.33) | ||
| ≥13.2 | 13.2 | 13 | 1.21 | (0.68, 2.16) | 1.30 | (0.70, 2.39) | ||
| Ptrend = 0.67 | Ptrend = 0.57 | |||||||
| Wine | ||||||||
| Year before baseline | ||||||||
| None | 0.0 | 91 | 1.00 | (reference) | 1.00 | (reference) | ||
| <11.1 | 3.3 | 99 | 1.08 | (0.81, 1.43) | 1.09 | (0.80, 1.50) | ||
| ≥11.1 | 11.1 | 63 | 1.50 | (1.08, 2.09) | 1.57 | (1.11, 2.22) | ||
| Ptrend = 0.01e | Ptrend = 0.01e | |||||||
| Ages 30–35 yearsc | ||||||||
| None | 0.0 | 90 | 1.00 | (reference) | 1.00 | (reference) | ||
| <11.1 | 3.3 | 112 | 1.19 | (0.90, 1.59) | 1.26 | (0.92, 1.71) | ||
| ≥11.1 | 11.1 | 29 | 1.21 | (0.78, 1.86) | 1.38 | (0.87, 2.19) | ||
| Ptrend = 0.36 | Ptrend = 0.16 | |||||||
| Ages 18–22 yearsd | ||||||||
| None | 0.0 | 167 | 1.00 | (reference) | 1.00 | (reference) | ||
| <11.1 | 3.3 | 63 | 1.11 | (0.82, 1.50) | 1.17 | (0.84, 1.63) | ||
| ≥11.1 | 11.1 | 8 | 1.42 | (0.69, 2.91) | 1.63 | (0.76, 3.50) | ||
| Ptrend = 0.28 | Ptrend = 0.15 | |||||||
| Liquor | ||||||||
| Year before baseline | ||||||||
| None | 0.0 | 169 | 1.00 | (reference) | 1.00 | (reference) | ||
| <15.0 | 4.5 | 68 | 1.09 | (0.82, 1.45) | 1.06 | (0.78, 1.44) | ||
| ≥15.0 | 15.0 | 16 | 0.87 | (0.52, 1.47) | 0.82 | (0.48, 1.39) | ||
| Ptrend = 0.80 | Ptrend = 0.56 | |||||||
| Ages 30–35 yearsc | ||||||||
| None | 0.0 | 124 | 1.00 | (reference) | 1.00 | (reference) | ||
| <15.0 | 4.5 | 93 | 1.07 | (0.81, 1.41) | 1.04 | (0.77, 1.40) | ||
| ≥15.0 | 15.0 | 14 | 0.77 | (0.44, 1.35) | 0.75 | (0.42, 1.36) | ||
| Ptrend = 0.52 | Ptrend = 0.44 | |||||||
| Ages 18–22 yearsd | ||||||||
| None | 0.0 | 164 | 1.00 | (reference) | 1.00 | (reference) | ||
| <15.0 | 4.5 | 69 | 0.99 | (0.74, 1.32) | 0.94 | (0.68, 1.29) | ||
| ≥15.0 | 15.0 | 5 | 0.62 | (0.25, 1.52) | 0.49 | (0.19, 1.26) | ||
| Ptrend = 0.39 | Ptrend = 0.17 | |||||||
a Adjusted for race, total energy intake, parity, oral contraceptive use, strenuous exercise, and menopausal status/hormone therapy use; stratified by age at baseline
b Additionally adjusted for consumption of other alcohol types in the same time period
c Among women over age 35 years at baseline with non-missing data on alcohol consumption at ages 30–35 years
d Among women over age 22 years at baseline with non-missing data on alcohol consumption at ages 18–22 years
ep for non-linearity of trend > 0.05