Table 3.
Relative risks (RRs) and 95% confidence intervals (CIs) for associations between patterns of drinking specific types of alcohol and risk of ovarian cancer
| Alcohol type | Time period | Drinking pattern | Cases (n) | RRa | 95% CIa | RRb | 95% CIb |
|---|---|---|---|---|---|---|---|
| Total alcohol | |||||||
| Age 30–35 years and the year before baselinec | |||||||
| Never | 49 | 1.00 | (reference) | — | |||
| Steady moderate | 118 | 1.25 | (0.89, 1.76) | — | |||
| Decreasing | 29 | 1.06 | (0.67, 1.68) | — | |||
| Increasing | 27 | 1.10 | (0.68, 1.77) | — | |||
| Steady heavy | 8 | 1.32 | (0.62, 2.82) | — | |||
| Age 18–22 years and the year before baselined | |||||||
| Never | 55 | 1.00 | (reference) | — | |||
| Steady moderate | 70 | 1.07 | (0.74, 1.53) | — | |||
| Decreasing | 24 | 1.06 | (0.65, 1.72) | — | |||
| Increasing | 86 | 1.30 | (0.92, 1.84) | — | |||
| Steady heavy | 3 | 1.87 | (0.58, 6.04) | — | |||
| Year before baseline | |||||||
| 0 days/week | 77 | 1.00 | (reference) | — | |||
| 1 to 4 days/week | 98 | 1.25 | (0.92, 1.69) | — | |||
| 5 to 7 days/week, ≤ 20 g/day | 30 | 1.36 | (0.88, 2.08) | — | |||
| 5 to 7 days/week, > 20 g/day | 18 | 1.14 | (0.68, 1.93) | — | |||
| Beer | |||||||
| Age 30–35 years and the year before baselinec | |||||||
| Never | 163 | 1.00 | (reference) | 1.00 | (reference) | ||
| Steady moderate | 26 | 0.80 | (0.53, 1.21) | 0.73 | (0.47, 1.13) | ||
| Decreasing | 25 | 0.94 | (0.62, 1.44) | 0.88 | (0.57, 1.38) | ||
| Increasing | 17 | 1.08 | (0.65, 1.79) | 0.99 | (0.59, 1.66) | ||
| Steady heavy | 0 | — | — | ||||
| Age 18–22 years and the year before baselined | |||||||
| Never | 159 | 1.00 | (reference) | 1.00 | (reference) | ||
| Steady moderate | 24 | 1.06 | (0.68, 1.64) | 1.02 | (0.64, 1.62) | ||
| Decreasing | 34 | 0.95 | (0.65, 1.38) | 0.92 | (0.61, 1.37) | ||
| Increasing | 21 | 0.77 | (0.49, 1.22) | 0.71 | (0.44, 1.14) | ||
| Steady heavy | 0 | — | — | ||||
| Year before baselinee | |||||||
| 0 days/week | 199 | 1.00 | (reference) | 1.00 | (reference) | ||
| 1 to 4 days/week | 40 | 0.98 | (0.70, 1.39) | 0.79 | (0.53, 1.16) | ||
| 5 to 7 days.week | 1 | 0.33 | (0.05, 2.37) | 0.36 | (0.05, 2.59) | ||
| Ptrend = 0.30 | Ptrend = 0.14 | ||||||
| Wine | |||||||
| Age 30–35 years and the year before baselinec | |||||||
| Never | 60 | 1.00 | (reference) | 1.00 | (reference) | ||
| Steady moderate | 65 | 1.15 | (0.80, 1.64) | 1.19 | (0.80, 1.77) | ||
| Decreasing | 34 | 1.25 | (0.82, 1.92) | 1.32 | (0.82, 2.11) | ||
| Increasing | 53 | 1.25 | (0.86, 1.82) | 1.29 | (0.86, 1.93) | ||
| Steady heavy | 19 | 1.54 | (0.91, 2.62) | 1.75 | (1.00, 3.04) | ||
| Age 18–22 years and the year before baselined | |||||||
| Never | 71 | 1.00 | (reference) | 1.00 | (reference) | ||
| Steady moderate | 29 | 0.98 | (0.63, 1.52) | 1.01 | (0.62, 1.63) | ||
| Decreasing | 20 | 1.48 | (0.89, 2.45) | 1.73 | (1.00, 2.99) | ||
| Increasing | 113 | 1.29 | (0.95, 1.74) | 1.38 | (0.99, 1.92) | ||
| Steady heavy | 5 | 2.47 | (0.99, 6.19) | 2.76 | (1.09, 7.00) | ||
| Year before baselinee | |||||||
| 0 days/week | 91 | 1.00 | (reference) | 1.00 | (reference) | ||
| 1 to 4 days/week | 97 | 1.19 | (0.89, 1.60) | 1.23 | (0.89, 1.71) | ||
| 5 to 7 days.week | 37 | 1.34 | (0.91, 1.98) | 1.45 | (0.96, 2.20) | ||
| Ptrend = 0.18 | Ptrend = 0.11 | ||||||
| Liquor | |||||||
| Age 30–35 years and the year before baselinec | |||||||
| Never | 110 | 1.00 | (reference) | 1.00 | (reference) | ||
| Steady moderate | 47 | 1.13 | (0.80, 1.60) | 1.12 | (0.76, 1.63) | ||
| Decreasing | 50 | 1.04 | (0.74, 1.46) | 0.97 | (0.67, 1.41) | ||
| Increasing | 21 | 1.11 | (0.69, 1.77) | 1.04 | (0.63, 1.70) | ||
| Steady heavy | 3 | 0.49 | (0.15, 1.54) | 0.46 | (0.15, 1.49) | ||
| Age 18–22 years and the year before baselined | |||||||
| Never | 126 | 1.00 | (reference) | 1.00 | (reference) | ||
| Steady moderate | 32 | 1.12 | (0.76, 1.66) | 1.10 | (0.71, 1.69) | ||
| Decreasing | 35 | 0.84 | (0.57, 1.23) | 0.76 | (0.50, 1.15) | ||
| Increasing | 44 | 0.98 | (0.69, 1.38) | 0.92 | (0.64, 1.33) | ||
| Steady heavy | 1 | 0.80 | (0.11, 5.77) | 0.69 | (0.10, 5.04) | ||
| Year before baselinee | |||||||
| 0 days/week | 169 | 1.00 | (reference) | 1.00 | (reference) | ||
| 1 to 4 days/week | 57 | 1.13 | (0.83, 1.53) | 1.10 | (0.78, 1.55) | ||
| 5 to 7 days.week | 13 | 1.00 | (0.57, 1.78) | 0.73 | (0.35, 1.51) | ||
| Ptrend = 0.92 | Ptrend = 0.44 | ||||||
a Adjusted for race, total energy intake, parity, oral contraceptive use, strenuous exercise, and menopausal status/hormone therapy use; stratified by age at baseline
b Additionally adjusted for drinking patterns of other alcohol types across the same time periods
c Among women over age 35 years at baseline with non-missing data on alcohol consumption at ages 30–35 years
d Among women over age 22 years at baseline with non-missing data on alcohol consumption at ages 18–22 years
e Excluding women with missing data on number of drinking days per week