Figure 8.

Rates of BrdUrd incorporation into T cells of nine patients who had viral loads <50 RNA copies/ml plasma for longer than 1 year were determined pretermination and 5 weeks posttermination of HAART. Increases in the mean fraction (A) and number (B) of dividing CD4⁺ and CD8⁺ T cells were observed after cessation of HAART. (C) Similar increases in proliferation were observed in both the blood and lymph node in the two patients in whom both compartments were examined pretermination (○) and 5 weeks posttermination (□) of HAART. (D) The nine patients above each reinitiated HAART, and BrdUrd incorporation into T cells was determined pre-HAART and 8 weeks post-HAART. Error bars = SEM. P values were determined by using the Wilcoxon Signed Rank Test and reflect comparisons between week 0 and week 5 or 8.