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. 2000 Nov 28;97(25):13790–13795. doi: 10.1073/pnas.250483097

Figure 4.

Figure 4

Effects of wild-type and 3A-2 mutant poliovirus infections on antigen presentation to CTL. Chimpanzee target cells were infected with wild-type vaccinia (wt-VV), rVV-NS3/4, wild-type (wt) poliovirus, 3A-2 mutant poliovirus, or coinfected with rVV-NS3/4 and rVV-GFP; rVV-NS3/4 and rVV-3A,GFP; rVV-NS3/4 and wild-type poliovirus, or rVV-NS3/4 and 3A-2 poliovirus. At 12 h after infection, target cells were incubated for 4 h with T14 CTL at an effector/target ratio of 1:1. Granzyme A secretion into the supernatants was determined by enzymatic assay. Data are presented as the means of triplicate samples, and the standard deviations are indicated.