Figure 3. Neuron-specific restoration of SH2B1 corrects energy imbalance in SH2B1^KO mice.

(A) Food intake in WT, SH2B1^Tg, SH2B1^KO, and SH2B1^TgKO-437 mice at age 14–15 weeks. (B) O₂ consumption and CO₂ production in WT, SH2B1^Tg, SH2B1^KO, and SH2B1^TgKO-437 mice at age 16–17 weeks. *P < 0.05.