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(A) SH2B1Tg-437 males and WT littermates were fed an HFD at age 7 weeks, and body weight was monitored weekly. (B) Fat content of SH2B1Tg-437 males and WT littermates fed an HFD for 9 weeks. (C) Plasma leptin levels in SH2B1Tg-437 males and WT littermates fed an HFD for 10 weeks. *P < 0.05.
