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. Author manuscript; available in PMC: 2007 Jan 10.
Published in final edited form as: Development. 2007 Jan;134(1):177–187. doi: 10.1242/dev.02706

Fig. 3.

Fig. 3

a selective antagonist of cyp26 enzymes recapitulates the cyp26a1; b1;c1 phenotype.

RNA in situs with the markers described in Fig. 2. Compared to DMSO-treated controls (A,C,E), treatment with 10 μM R115866 (B,D,F) causes an anterior shift of hoxb1a (arrowhead in A,B) and hoxd4 (arrowhead in C,D) toward the presumptive cerebellum marked by en3 (red in A,B) and by pax2a (brackets in C-F). This effect of R115866 is reversed by co-treatment with 10 μM DEAB (E,F). Scale bar: 100 μm. Bar in A is for A and B; Bar in C is for C-F.