Figure 5.

PSGL-Ig infusion decreases the number of microparticles and prolongs the clotting time in plasma of ΔCT mice. (A) Number of microparticles present in 40 μl of ΔCT plasma, before (open bars) and after (filled bars) two infusions of PSGL-Ig and control-Ig as described in Materials and Methods. *, P < 0.05, determined by paired t test. (B) Clotting time of plasma obtained at the end of the experiment was significantly longer in mice treated with PSGL-Ig (filled bar) than in control-Ig-treated group (striated bar), P < 0.05.