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The combined pressure and temperature dependencies of the reductive half-reaction of MR with NADH and NAD2H. (A) Plot of kred versus p for the reaction with both cofactors at the limits of the temperature range, 5°C and 40°C. The solid lines are fits to Eq. 1; note the log scale for k. (B) Eyring plots of the reaction at atmospheric pressure and at 2 kbar. (C) The combined effect of pressure and temperature on the resulting KIE.
