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. 2004 Nov;63(Suppl 2):ii92–ii95. doi: 10.1136/ard.2004.028332

Figure 2.

Figure 2

 Not all fibroblasts are the same. Fibroblasts from the rheumatoid, or normal synovium look different from fibroblasts from the skin and express different patterns of adhesion and matrix molecules compared with fibroblasts derived from the skin. Pictures (left) show fibroblasts labelled for fibronectin with nuclei counter stain. A range of markers (CD90, collagen III, CD44, VCAM-1 (CD106), CD40, and fibronectin) have been used to label either rheumatoid, normal synovium, or skin fibroblasts which have then been examined by flow cytometry.