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Inhibitory agonists activate potassium channels in gastrointestinal smooth muscles. VIP, vasoactive intestinal peptide; cAMP, cyclic adenosine monophosphate; cGMP, cyclic guanosine monophosphate; SK, small conductance Ca2+ activated K+ channel; SR, sarcoplasmic reticulum; P2Y, purinergic receptor type P2Y; DR, delayed rectifier; BK, large conductance Ca2+ activated K+ channel.
