Table 5.

Genotype distribution of the GPIba VNTR and Kozak polymorphisms between the infarct and non-infarct patient groups

	VNTR						Kozak
	AC	BC	BD	CC	CD	DD	TT*	TC	CC
Infarct group (n=88)	0 (0.0)	6 (6.8)	3 (3.4)	69 (78.4)	8 (9.1)	2 (2.3)	75 (85.2)	11 (12.5)	2 (2.3)
Non-infarct group (n=168)	1 (0.6)	23 (13.6)	2 (1.2)	113 (67.3)	27 (16.1)	2 (1.2)	113 (67.3)	55 (32.7)	0 (0.0)

Values are n (%).

No significant association was found between the VNTR genotypes and myocardial infarction (p=0.60). Considering the CC genotype v all other VNTR genotypes, there was a marginal association (p=0.059, OR 1.8, 95% CI 0.94 to 3.48).

*A significant association was found between the Kozak TT genotype and myocardial infarction (p<0.001, OR 2.10, 95% CI 1.11 to 4.02); the TT v TC+CC Kozak genotype also showed a significant association with myocardial infarction (p=0.002, OR 2.81, 95% CI 1.37 to 5.82).

CI, confidence interval; OR, odds ratio; VNTR, variable number tandem repeat.