Figure 3.

Scatter plots showing the effect of GR79236 on left ventricular function at rest and during exercise as a function of the response during the first exercise test following placebo. (A) Change in regional ejection fraction (EF) at rest. GR79236 decreased resting function of ischaemic sectors, but had no consistent effect on non-ischaemic sectors. (B) Change in regional EF during exercise. GR79236 increased exercise function of ischaemic sectors, but decreased exercise function of non-ischaemic sectors. (C) Change in global EF at rest. GR79236 tended to decrease resting global EF in patients whose EF decreased during exercise following placebo, but had no consistent effect in those whose EF increased. (D) Change in global EF during exercise. GR79236 tended to increase exercise global EF in patients whose EF decreased during exercise following placebo, but decreased exercise EF in those whose EF increased.