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. 2002 Mar;87(3):270–275. doi: 10.1136/heart.87.3.270

Table 1.

Distribution of pro-left ventricular hypertrophy (LVH) genotypes in patients with hypertrophic cardiomyopathy (HCM) and controls

ACE AGT AGTR1 CMA CYP11B2
HCM (n=26)
II=6 CC=6 CC=1 AA=6 CC=4
ID=14 TC=17 AC=10 GG=13 TC=14
DD=6 TT=3 AA=15 AG=7 TT=8
    Allele frequency I=0.5 C=0.54 C=0.22 A=0.46 C=0.41
    Prevalence of pro-LVH genotype D=0.5 T=0.46 A=0.78 G=0.54 T=0.59
DD=23% CC=23% CC=4% AA=23% CC=15%
Control (n=100)
II=28 CC=17 CC=9 AA=23 CC=23
ID=43 TC=58 AC=34 GG=58 TC=40
DD=29 TT=25 AA=57 AG=19 TT=37
    Allele frequency I=0.5 C=0.46 C=0.26 A=0.52 C=0.43
D=0.5 T=0.54 A=0.74 G=0.48 T=0.57
    Prevalence of pro-LVH genotype DD=29% CC=17% CC=9% AA=23% CC=23%

ACE, angiotensin converting enzyme gene; AGT, angiotensinogen gene; AGTR1, angiotensin II receptor type 1 gene; CMA, chymase A gene; CYP11B2, aldosterone synthase gene.