Table 1.

Changes in echocardiographic measurements during preload altering manoeuvres

Variable	Baseline	Stage 1	Stage 2	Stage 3
LVEDV (ml)*	198.6 (132.2)	242.2 (186.2)	212.1 (163.0)	188.1 (132.9)
Left atrial area (mm2)†	22.4 (8.6)	23.9 (10.0)	21.7 (9.6)	20.1 (7.7)
E wave (cm/s)‡	82.4 (33.1)	84.6 (32.2)	71.9 (25.9)	72.8 (20.2)
EDTV (cm/s)§	10.3 (3.5)	10.7 (3.1)	10.7 (3.4)	11.1 (3.7)
Systolic blood pressure (mm Hg)*	126.4 (18.6)	122.9 (16.9)	118.1 (21.0)	103.2 (21.5)

Values are mean (SD).

p Values: stages 1–3 v baseline: *p=0.001; †p=0.003; ‡p=0.01; §p=NS (p>0.05).

Stage 1, Trendelenberg manoeuvre; stage 2, reverse Trendelenberg manoeuvre; stage 3, amyl nitrate inhalation.

E, left ventricular early mitral inflow velocity; EDTV, early diastolic velocity; LVEDV, left ventricular end diastolic volume.